VitaminNZ Blog

Wednesday, January 13, 2016

Benefits of Glucosamine with MSM

Benefits of Glucosamine with MSM

Benefits of Glucosamine with MSM
Why take Glucosamine tablets?
Glucosamine is vital for building cartilage. Cartilage is a flexible, tough connective tissue found in several areas of the body. This fine, rubbery tissue functions as padding, a cushion for bones and joints.

Glucosamine plays a crucial role in incorporating sulfur into cartilage.

As we age, glucosamine levels go down, which can lead to eventual joint deterioration.

What is Glucosamine?

Glucosamine is derived from the shells of shrimps, lobster and crabs. It is a basic building block for cartilage, synovial fluid and other connective tissues, which are needed for healthy structure integrity, and function of joints and optimum mobility.

What is MSM?

MSM (Methylsulfonylmethane) is a bioavailable sulfur. Sulfur is a necessary component that works in conjunction with Glucosamine to provide the building blocks of collagen, an important component of healthy joints and connective tissue.

The primary property of MSM is to make the walls of the cells permeable. When the cell walls become permeable, the toxins, unwanted materials, and free radicals are easily and efficiently removed or flushed out of the cells. Another property of MSM is to block parasites from attaching themselves to the lungs and digestive system’s mucous membranes and finally help in reducing inflammation. Reduction of the inflammation is the main reason why MSM is prescribed for rheumatoid arthritis. It is a natural anti-inflammatory and analgesic. When combined with Glucosamine, it helps in reducing disfiguring and inflammation within the joints which is the main characteristic of rheumatoid arthritis. It is also believed that other than just relieving the pain and inflammation, it also helps in removing toxins from joints which might lead to joint problems. 

Glucosamine and MSM is an effective supplement combination that helps support maximum flexibility, range of motion, joint lubrication and maintenance for healthy cartilage and connective tissue. 

What proof do you have that Glucosamine with MSM works?

That’s always a problem with any comments made on any subject! One article will say one thing and another may even contradict those comments…

Researchers conducted a 12-week double-blind clinical trial on 118 patients with mild to moderate osteoarthritis. Three times a day, one group took 500 mg of glucosamine sulfate, one group took 500 mg of MSM and one group took both. In the glucosamine-only group, pain scores fell from 1.74 to 0.65; in the MSM only group, pain scores fell from 1.53 to 0.74; and in the combination group, pain scores fell from 1.7 to 0.36, equalling about twice the level of improvement in pain and inflammation compared to either glucosamine or MSM alone. 

Can you get glucosamine naturally from foods?

Glucosamine supplements are made from the shells of shellfish, so there are no natural food source for glucosamine.

What dosage should we take?

The typical dosage of glucosamine in most studies is 500mg of glucosamine taken 3 times a day.

An MSM dosage of 2,000 mg. is recommended divided into 3 dosages every day.

 Some experts say to take glucosamine with food to prevent any possibility of stomach upset.

This article and associated info has been drawn from several reference articles with additional notes and wording by Vitamin NZ.


Clin Drug Investig. 2004;24(6):353-363.